The effect of supine bedrest upon alveolar-arterial oxygen gradients and intrapulmonary shunting in normal man

The normal alveolar-arterial oxygen-tension gradient in man.

2. The gradient increased with age and with inspired O2 concentration up to 60%. Above 60%, during normal breathing, there was no significant change in gradient. 3. Breathing 100% 0, in deep breaths decreased the gradient in all age-groups, significantly so in subjects of 50 years and younger. The remaining gradient was due to anatomical venous shunt. 4. When this anatomical shunt was allowed f...

Alveolar and arterial oxygen tensions and the significance of the alveolar-arterial oxygen tension difference in normal men.

Changes in Intrapulmonary Shunting

We would like to offer the following comments concerning the interesting paper by Shapiro et al (Chest 1980; 77:138). Even though we agree, in general terms, with their statement that venous admixture ( va/Qt) should increase when a patient breathes 100 percent 02, measured either by Berggien’s classic methodl or with the inert gases technique,2 we have observed that it does not always do so be...

the tragedy of modern man in arthur millers world

what miller wants is a theatre of heightened consciousness. he speaks of two passions in a man, the passion to "feel" and the passion "know". he belives that we can have more of the latter. he says: drama is akin to the other inventions of man in that it ought to help us know more and not merely to spend our feelings. the writing of the crucible shows us that he is trying to give more heightene...

The effect of lipemia upon tissue oxygen tension in man.

SUBSEQUENT to the observation that the intravenous infusion of fat emulsion caused a decrease in the nmyocardial oxygentension of dogs having anl experimentally produced nmyocardial infaretion, it was shown that the hyperlipemia following a large fat meal may precipitate an attack of angina pectoris in patients with severe coronary artery disease.1-3 These attacks of angina developed about 5 ho...